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HRPP Operations Manual

  • The HRPP Operations Manual details the policies and processes for investigators, students, and staff that govern the conduct and review of human subjects research under the U-M Human Subject Protection Program (HRPP) at the University of Michigan.

    • HRPP Operations Manual Describes the overarching rules governing the University of Michigan's Human Research Protection Program (HRPP) and outlines responsibilities, processes, and guidelines for the U-M investigators, the institutional review boards (IRBs), administrators, and others under the HRPP. [PDF]  Last updated:  April 2023